SimuRg: Building, Fitting and Evaluating PK/PD Modeles
Provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.
| Version: |
0.2.0 |
| Depends: |
R (≥ 3.5) |
| Imports: |
cluster, dplyr, fastDummies, forcats, ggplot2, jsonlite, MASS, philentropy, purrr, readr, recipes, rlang, rxode2, scales, stringr, synthpop, sys, tibble, tidyr, uwot, zoo, lhs, sensitivity, ppcor, withr |
| Suggests: |
GGally, testthat (≥ 3.0.0) |
| Published: |
2026-05-19 |
| DOI: |
10.32614/CRAN.package.SimuRg (may not be active yet) |
| Author: |
Victor Sokolov [cph, aut],
Anna Mikhailova [cre],
Yaroslav Ugolkov [aut],
Anatoly Pokladyuk [aut],
Alina Melnikova [aut],
Victoria Kulesh [aut] |
| Maintainer: |
Anna Mikhailova <anna.mikhailova at msdecisions.tech> |
| License: |
MIT + file LICENSE |
| NeedsCompilation: |
no |
| Materials: |
README, NEWS |
| CRAN checks: |
SimuRg results |
Documentation:
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