Time to Event Outcome in Experimental Designs of Pre-Clinical Studies

Documentation for package ‘PDXpower’ version 1.0.2

animals1	Simulated preliminary animals uncensored data
animals2	Simulated preliminary animals censored data
plotpower	A function to generate a four-panel power curve under specified number of PDX lines and number of individuals per PDX lines per treatment
PowANOVA	A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a prior knowledge of median survival
PowANOVADat	A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a preliminary dataset
PowerTable	A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment.
PowFrailty	A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a prior knowledge of median survival
PowFrailtyDat	A function to obtain a power table with the combination of various number of PDX lines and number of individuals per PDX lines per treatment based on a preliminary dataset
print.PowerTable	Print PowerTable
SimPDXdata	A function to calculate the power under pre-specified effect size, variance, and correlation using Monte Carlo sampling scheme by fitting ANOVA fixed effects model, ANOVA random effects model, Cox model, and frailty model.