normalize.loess {codelink} | R Documentation

## Normalized chips using cyclic loess.

### Description

Takes a matrix and apply cyclic loess normalization. It is based in normalize.loess from package affy but supports NA.

### Usage

            normalize.loess(mat, subset = sample(1:(dim(mat)[1]),
                min(c(5000, nrow(mat)))), epsilon = 10^-2, maxit = 1,
                log.it = TRUE, verbose = TRUE, span = 2/3,
                family.loess = "symmetric")

### Arguments

`mat` | a matrix with columns containing the values of the chips to normalize.
`subset` | a subset of the data to fit a loess to.
`epsilon` | a tolerance value (supposed to be a small value - used as a stopping criterium).
`maxit` | maximum number of iterations.
`log.it` | logical. If `TRUE` it takes the log2 of `mat`
`verbose` | logical. If `TRUE` displays current pair of chip being worked on.
`span` | parameter to be passed the function `loess`
`family.loess` | parameter to be passed the function `loess`. `"gaussian"` or `"symmetric"` are acceptable values for this parameter.

### Details

### Value

A matrix of normalized values.

### Note

### Author(s)

Diego Diez

### See Also

### Examples

    #       mat <- matrix(sample(500), 100, 5)
    #       mat <- normalize.loess(mat)

[Package codelink version 1.2.2 Index]