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singIST

This is the released version of singIST; for the devel version, see singIST.

comparative single-cell transcriptomics between disease models and a human condition


Bioconductor version: Release (3.23)

Provides with toolkits to implement a full singIST analysis with pseudobulked Seurat objects of disease models and human data.

Author: Aitor Moruno-Cuenca [aut, cre] ORCID iD ORCID: 0009-0009-8133-2552 , Dr. Sergio Picart-Armada [rev] ORCID iD ORCID: 0000-0002-6426-8204 , Dr. Alexandre Perera-Lluna [ths] ORCID iD ORCID: 0000-0001-6427-851X , Dr. Francesc Fernández-Albert [ths] ORCID iD ORCID: 0000-0001-5561-0701

Maintainer: Aitor Moruno-Cuenca <morunoaitor at gmail.com>

Citation (from within R, enter citation("singIST")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("singIST")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("singIST")
singIST Vignette HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Classification, SingleCell, Software, Transcriptomics
Version 1.0.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.6.0)
Imports msigdb, GSEABase, checkmate, stats, asmbPLS, BiocParallel, stringr, FactoMineR, Seurat, SeuratObject, biomaRt, data.table, purrr, SingleCellExperiment, SummarizedExperiment, scran, scuttle, missMDA, S4Vectors
System Requirements
URL https://github.com/DataScienceRD-Almirall/singIST
Bug Reports https://github.com/DataScienceRD-Almirall/singIST/issues
See More
Suggests testthat (>= 3.0.0), BiocStyle, knitr, qpdf, utils, RcppAlgos, glmGamPoi, methods, sp
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package singIST_1.0.0.tar.gz
Windows Binary (x86_64) singIST_0.99.85.zip
macOS Binary (big-sur-x86_64) singIST_1.0.0.tgz
macOS Binary (sonoma-arm64) singIST_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/singIST
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/singIST
Bioc Package Browser https://code.bioconductor.org/browse/singIST/
Package Short Url https://bioconductor.org/packages/singIST/
Package Downloads Report Download Stats