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deltaCaptureC

This is the released version of deltaCaptureC; for the devel version, see deltaCaptureC.

This Package Discovers Meso-scale Chromatin Remodeling from 3C Data


Bioconductor version: Release (3.23)

This package discovers meso-scale chromatin remodelling from 3C data. 3C data is local in nature. It givens interaction counts between restriction enzyme digestion fragments and a preferred 'viewpoint' region. By binning this data and using permutation testing, this package can test whether there are statistically significant changes in the interaction counts between the data from two cell types or two treatments.

Author: Michael Shapiro [aut, cre] ORCID iD ORCID: 0000-0002-2769-9320

Maintainer: Michael Shapiro <michael.shapiro at crick.ac.uk>

Citation (from within R, enter citation("deltaCaptureC")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("deltaCaptureC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("deltaCaptureC")
Delta Capture-C HTML R Script
Reference Manual PDF
LICENSE Text

Details

biocViews BiologicalQuestion, Software, StatisticalMethod
Version 1.26.0
In Bioconductor since BioC 3.10 (R-3.6) (7 years)
License MIT + file LICENSE
Depends R (>= 3.6)
Imports IRanges, GenomicRanges, SummarizedExperiment, ggplot2, DESeq2, tictoc
System Requirements
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Suggests knitr, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package deltaCaptureC_1.26.0.tar.gz
Windows Binary (x86_64) deltaCaptureC_1.26.0.zip
macOS Binary (big-sur-x86_64) deltaCaptureC_1.26.0.tgz
macOS Binary (sonoma-arm64) deltaCaptureC_1.26.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/deltaCaptureC
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/deltaCaptureC
Bioc Package Browser https://code.bioconductor.org/browse/deltaCaptureC/
Package Short Url https://bioconductor.org/packages/deltaCaptureC/
Package Downloads Report Download Stats