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SingleR

This is the released version of SingleR; for the devel version, see SingleR.

Reference-Based Single-Cell RNA-Seq Annotation


Bioconductor version: Release (3.23)

Performs unbiased cell type recognition from single-cell RNA sequencing data, by leveraging reference transcriptomic datasets of pure cell types to infer the cell of origin of each single cell independently.

Author: Dvir Aran [aut, cph], Aaron Lun [ctb, cre], Daniel Bunis [ctb], Jared Andrews [ctb], Friederike Dündar [ctb]

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>

Citation (from within R, enter citation("SingleR")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SingleR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SingleR")
Annotating scRNA-seq data HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Annotation, Classification, Clustering, GeneExpression, SingleCell, Software, Transcriptomics
Version 2.14.1
In Bioconductor since BioC 3.10 (R-3.6) (7 years)
License GPL-3
Depends SummarizedExperiment
Imports methods, Matrix, BiocGenerics, S4Vectors, DelayedArray, stats, utils, Rcpp, beachmat(>= 2.27.3)
System Requirements C++17
URL https://github.com/SingleR-inc/SingleR
Bug Reports https://github.com/SingleR-inc/SingleR/issues
See More
Suggests testthat, knitr, rmarkdown, BiocStyle, BiocParallel, SingleCellExperiment, scrapper(>= 1.5.16), scRNAseq, ggplot2, pheatmap, grDevices, gridExtra, viridis, celldex
Linking To Rcpp, beachmat, assorthead(>= 1.3.5)
Enhances
Depends On Me OSCA.advanced, OSCA.basic, OSCA.multisample, OSCA.workflows, SingleRBook
Imports Me CellMentor, scTypeEval, singleCellTK, OSTA
Suggests Me Coralysis, scDiagnostics, scGraphVerse, sketchR, tidySingleCellExperiment
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SingleR_2.14.1.tar.gz
Windows Binary (x86_64) SingleR_2.14.1.zip
macOS Binary (big-sur-x86_64) SingleR_2.14.1.tgz
macOS Binary (sonoma-arm64) SingleR_2.14.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/SingleR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SingleR
Bioc Package Browser https://code.bioconductor.org/browse/SingleR/
Package Short Url https://bioconductor.org/packages/SingleR/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.23 Source Archive