ppipred {ppiData} | R Documentation |
The data in ppipred
are those provided by Liu et al
for S. cervisiae protein protein interactions.
data(ppipred)
A data frame with 20088 observations on the following 3 variables.
Gene1
Gene2
Probability
Liu et al discuss a method for estimating protein-protein interactions from existing data, across species. They have provided the data with the following description: “We compute domain-domain interaction probabilities from Y2H protein-protein interactions, and then use these domain-domain interaction probabilities to compute the interaction probability between every pair of proteins. The prediction results with a false positive rate fp=3E-4 and a false negative rate fn=0.85 are listed blow.”
http://bioinformatics.med.yale.edu/interaction/
Inferring protein-protein interactions through high-throughput interaction data from diverse organisms, Y. Liu, N. Liu and H. Zhao, Bioinformatics, 2005, 21, 3279-3285.
data(ppipred)